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☆ A woman couldn't understand why she wasn't losing weight after trying diets, exercise, and medication. A test revealed she was missing crucial gut microbes.
▼ + stars: | 2024-05-09 | by ( Kim Schewitz | ) www.businessinsider.com time to read: +5 min

Kimmie Gilbert couldn't seem to lose weight despite trying diets, exercise, and medication. Research suggests that gut microbiome composition might play a role in a person's weight. AdvertisementKimmie Gilbert has one pressing question: "What in the world are y'all eating that I'm not eating that causes y'all to lose weight and not me?" In 2019, health tech had a global market value of approximately $350 billion, according to McKinsey. A microbe called Prevotella, which is associated with weight loss, wasn't found at all in her gut.

Persons: Kimmie Gilbert couldn't, Gilbert, —, Kimmie Gilbert, y'all, Eran Segal, Annie Gupta, Goodman, Rob Knight, Jack Gilbert, wasn't, Gupta, Prevotella, Segal Organizations: Service, Netflix, McKinsey, BMI, Weizmann Institute of Science, UCLA, Luskin, UC San Diego Locations: New Orleans

☆ Biotech startup Seed Health is betting its profits on AI-powered medical science
▼ + stars: | 2024-04-11 | by ( Natalie Rose Goldberg | ) www.cnbc.com time to read: +7 min

On Thursday, Seed Health launched CODA, a computational biology platform funded by its consumer business profitability. Seed Health has been in the business of microbiome scientific breakthroughs since its founding in 2015, but its biggest success to-date may have been becoming profitable as a bioscience startup. Katz's co-founder and co-CEO at Seed Health, Raja Dhir, said CODA and the accompanying data set will help to standardize microbiome science methods, which has long been an issue in the field. CODA's first applications are in metabolic health, brain health, longevity, and menopause, research areas chosen because they have already been identified as areas of human health where early CODA data displayed the strongest evidence. Seed Health has been working on several efforts around pioneering microbiome science for human and planetary health, and many in the field believe the approach is destined to have wider applications.

Persons: Katz, Ara Katz, Eran Segal, Eric Topol, transcriptome, Katz's, Raja Dhir, Dhir, Arpana Gupta, Goodman, There's, Segal, Joseph Petrosino, Petrosino Organizations: Seed, Seed Health, CNBC, Weizmann Institute of Science, Scripps Research Institute, UCLA, Luskin Microbiome, Baylor College of Medicine, Center, Metagenomics, Microbiome Research

☆ The Israeli-Palestinian Conflict and the Long Shadow of 1948
▼ + stars: | 2024-02-01 | by ( Emily Bazelon | A Discussion Moderated Emily Bazelon | ) www.nytimes.com time to read: +18 min

In 1948, Jews realized their wildly improbable dream of a state, and Palestinians experienced the mass flight and expulsion called the Nakba, or catastrophe. It’s only in 1948 that the Arabs become Palestinians and the Jews become Israelis. Many Jews became lower-level officers during World War II, and they brought their new military expertise to the 1948 war. Zoltan Kluger/GPO, via Getty Images Palestinian bombers destroyed buildings on Ben Yehuda Street in Jerusalem in March 1948. Bettmann/Getty Images A Palestinian refugee cut off from her home by the border established after the 1948 war.

Persons: Matson, —, Khalil Raad, Yaakov Ben Dov Delegates, Haj Amin al, Husseini, ”, It’s, Avraham Avinu, David, Fox, King David Hotel, David Ben, Gurion, “, Hitler, Hans Pinn, Abd al, Qadir al, Chalil, Zoltan Kluger, Ben Yehuda, Hugo H, Mendelsohn, John Phillips, Palestine ”, UNSCOP, Bettmann, Ruth Orkin, David Seymour, Jordan, Israel, Abdullah, Nadim, Leena Dallasheh, Abigail Jacobson, Moshe Naor, ” Derek Penslar, ” Itamar Rabinovich, Salim Tamari, Emily Bazelon, Herzl, Faisal Al, Hashemi, James Russell &, Bain, Jabotinsky, Abraham Pisarek, Weizmann, Heinrich Hoffmann Organizations: Congress, Institute for Palestine, Palestinian, . Institute for Palestine, Matson, Palestine, Getty, of Congress British, Peel, Zionist, Jewish, British Armed Forces, Allied, King, of Congress Women, Hulton, Biltmore, British, Agence France, Getty Images, Refugees, West Bank, Shutterstock, United Nations, League of Nations, United, United Nations Jewish, Madver, The, Palestine Studies, Columbia University, Columbia University , New York University, Rice University, Islamic, Hebrew University of Jerusalem, Center for Jewish Studies, Harvard University, Tel Aviv University, Birzeit University, Institute for Palestine Studies, The New York Times Magazine, James Russell & Sons, of Congress, Israel, Ben, General Photographic Agency, Society, International Affairs Locations: Palestine, City, Jerusalem, Canadian American, Israel, British, Jaffa, Damascus, Old City, Hebron, Safed, Europe, Arab, North Africa, New York City, Middle Eastern, Haifa, Cyprus, Jenin, U.S, United Nations, Iraq, Tel Aviv’s Lod, Lebanon, Eyal, el Bared, Egypt, Syria, Gaza, Tel Aviv, Ashdod, Palestinian, United States, Qatar, Iran, Columbia University ,, Nazareth, Israeli, Husseini

☆ Scientists create chimeric monkey with two sets of DNA
▼ + stars: | 2023-11-09 | by ( Katie Hunt | ) edition.cnn.com time to read: +7 min

CNN —Scientists based in China have created a monkey chimera with two sets of DNA, experimental work they say could ultimately benefit medical research and the conservation of endangered species. It’s the world’s first live birth of a primate chimera created with stem cells, the researchers said. Scientists have created mouse embryos that are part human, and in 2021, scientists reported that they had grown human-monkey chimeric embryos. In September, researchers reported that they had grown kidneys containing mostly human cells inside pig embryos. Then they selected a subset of cells to inject into genetically distinct 4- to 5-day-old embryos from the same monkey species.

Persons: —, ”, Miguel Esteban, chimeras, Zhen Liu, Liu, Jun Wu, hadn’t, Wu wasn’t, Jacob Hanna, ” Hanna, Penny Hawkins, “ Organizations: CNN —, Cell, Guangzhou Institute of Biomedicine, Chinese Academy of Sciences, Research, University of Texas Southwestern Medical Center, Weizmann Institute of Science, Royal Society for, National Academies of Sciences, Engineering, Medicine, Covid Locations: China, Health, Research Hangzhou, Israel, United States

☆ Lab models of human embryos raise hopes and concerns
▼ + stars: | 2023-10-26 | by ( Katie Hunt | ) edition.cnn.com time to read: +14 min

From the moment sperm fuses with an egg, human embryo development involves a string of complex and little understood processes. What happens during human embryo development, particularly in the crucial first month, remains largely unknown. However, 14 days is an important milestone because it is when permitted lab research on cultured human embryos routinely ends. He said, in the future, it might be possible to go as far as 40 days with human embryo models. Some in the field envision a “tipping point” wherein human embryo models might be afforded some protection like those surrounding human embryos, as scientific advances diminish the differences between the embryo models and their real-life counterparts.

Persons: CNN — It’s, ”, Jacob Hanna, demystify, they’ve, Hanna, “ It’s, ” Hanna, “, Peter Rugg, Gunn, it’s, …, Robin Lovell, Francis Crick, Naomi Moris, Francis Crick Institute’s, Moris, we’ve, ” Moris, It’s, Bobbie Farsides, ” Farsides Organizations: CNN, Weizmann Institute of Science, Weizmann Institute, Israel, Weizmann, Babraham Institute, International Society for Stem Cell Research, Stem Cell, Francis, Francis Crick Institute, Genetics, Development, ”, Sussex Medical School Locations: Israel, London, Brighton

☆ Israeli scientists create model of human embryo without eggs or sperm
▼ + stars: | 2023-09-07 | by ( ) www.reuters.com time to read: +3 min

The Israeli team emphasised that they were a long way from being able to create an embryo from scratch. "The question is, when does an embryo model become considered an embryo? At the moment we are really, really far off from that point," said team leader Jacob Hanna. "None of these models fully recapitulate natural human development but each adds to ways in which many aspects of human development can now be studied experimentally," she said. The study raises some ethical questions over the possibility of potential future manipulation in human embryo development, Hanna and others noted.

Persons: Mehmet Yunus Comar, Jacob Hanna, Hanna, Magdalena Żernicka, Goetz, Rami Amichay, Ari Rabinovitch, Mark Heinrich Our Organizations: Weizmann Institute of Science, Israel's Weizmann Institute of Science, International Society for Stem Cell Research, University of Cambridge, Thomson Locations: Rehovot, Israel, Boston

☆ Israeli Scientists Create Model of Human Embryo Without Eggs or Sperm
▼ + stars: | 2023-09-07 | by ( Sept. | At P.M. | ) www.usnews.com time to read: +3 min

REHOVOT, Israel (Reuters) - Scientists in Israel have created a model of a human embryo from stem cells in the laboratory, without using sperm, eggs or a womb, offering a unique glimpse into the early stages of embryonic development. "The question is, when does an embryo model become considered an embryo? At the moment we are really, really far off from that point," said team leader Jacob Hanna. "None of these models fully recapitulate natural human development but each adds to ways in which many aspects of human development can now be studied experimentally," she said. The study raises some ethical questions over the possibility of potential future manipulation in human embryo development, Hanna and others noted.

Persons: Jacob Hanna, Hanna, Magdalena Żernicka, Goetz, Rami Amichay, Ari Rabinovitch, Mark Heinrich Organizations: Israel's Weizmann Institute of Science, International Society for Stem Cell Research, University of Cambridge Locations: REHOVOT, Israel, Boston

☆ Scientists grew a model human embryo in a lab without a sperm or egg, bringing humans one step closer to understanding the secrets of how our bodies are built
▼ + stars: | 2023-09-07 | by ( Maiya Focht | ) www.businessinsider.com time to read: +3 min

Scientists used stem cells to create a model of an embryo in the lab without sperm or egg. Researchers brought us one step closer to understanding those early days by making a model of a human embryo in the lab, without using sperm or eggs. How scientists grew a model human embryo without a sperm or eggAn illustration of embryonic stem cells. Stem cells are cells that form other, more complex cell types depending on what messages the body sends them. Starting with stem cells, the researchers turned them into types of cells that make up a human embryo, from placenta to fetus.

Persons: Jacob Hanna, Hanna, aren't Organizations: Service, Weizmann Institute of Science, Mayo Clinic, BBC Locations: Wall, Silicon

☆ Scientists Debut Lab Models of Human Embryos
▼ + stars: | 2023-06-24 | by ( Carl Zimmer | ) www.nytimes.com time to read: +1 min

In its first week, a fertilized human egg develops into a hollow ball of 200 cells and then implants itself on the wall of the uterus. Over the next three weeks, it divides into the distinct tissues of a human body. And those crucial few weeks remain, for the most part, a black box. Dr. Hanna and a number of other biologists are trying to uncover those details by creating models of human embryos in the lab. They are coaxing stem cells to organize themselves into clumps that take on some of the crucial hallmarks of real embryos.

Persons: ”, Jacob Hanna, Hanna, Hanna’s Organizations: Weizmann Institute of Science Locations: Israel, Britain, United States, China

☆ BioNTech to develop, produce cancer drugs and vaccines in Jerusalem -Israel Fin Min
▼ + stars: | 2023-03-21 | by ( ) www.reuters.com time to read: 1 min

Companies BioNTech SE FollowJERUSALEM, March 21 (Reuters) - Germany's BioNTech SE (22UAy.DE) signed a preliminary deal to set up a facility to produce cancer-related drugs and vaccines in Jerusalem, Israel's Finance Ministry said on Tuesday. Under the memorandum of understanding, BioNTech will develop the drugs and vaccines using mRNA technology in the Har Hotzvim technology park. It will also set up a research centre at the Weizmann Institute in central Israel. Reporting by Steven Scheer Editing by Ari RabinovitchOur Standards: The Thomson Reuters Trust Principles.

☆ About 17 Americans die waiting for transplants each day. Scientists are trying to make more organs in 5 creative ways.
▼ + stars: | 2022-10-18 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +11 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute. Hanna started a company called Renewal Bio to pursue the possibility of turning stem cells into organs for transplants.

☆ 5 cutting-edge medical experiments could expand our organ supply, from gene-edited pigs to artificial embryos
▼ + stars: | 2022-09-24 | by ( Morgan Mcfall-Johnsen | ) www.businessinsider.com time to read: +10 min

Courtesy of Leilani GrahamIf pig organs turn out to be just as effective as human organs, she added, "That is more appealing to me than using marginal donors." While much of the shortage is driven by imperfect logistics and bureaucracy rather than supply, cutting-edge research could make organs — human, pig, or synthetic — more accessible in Graham's lifetime. If the technique works for human organs in the future, it could allow clinicians to preserve many more organs for donation after death. Changing organs' blood typeEnzymes are delivered to a lung inside a perfusion machine at Dr. Marcelo Cypel’s lab. Growing synthetic organs from stem cellsResearcher Stormy Chamberlain holds a tray of stem cells at the University of Connecticut's Stem Cell Institute.

☆ Peste jumătate din populația Israelului a fost vaccinată împotriva COVID-19 cu ambele doze
▼ + stars: | 2021-03-26 | by ( Diana Severin | ) www.zdg.md time to read: +1 min

Distribuirea vaccinului Pfizer Inc în Israel a început în decembrie 2020, cu eligibilitate extinsă la cetăţenii şi rezidenţii de peste 16 ani. Israelul a început să faciliteze blocarea la nivel național la sfârșitul lunii februarie. Majoritatea afacerilor și școlilor, precum și a aeroporturilor, și-au reluat treptat activitatea – cu limite de capacitate. Directorul general al Ministerului Sănătății, Hezi Levi, a declarat pentru Reuters că toți israelienii eligibili ar putea fi vaccinați complet până la sfârșitul lunii mai. Dar unii oficiali estimează în mod privat că 10% din populația eligibilă nu intenționează să se vaccineze.

Persons: Reuters, Segal, Hezi Levi Organizations: Pass, Ministerului Sănătății, Israelul, Weizmann Locations: Israel

☆ Pentru prima dată în istorie, masa tuturor construcţiilor realizate de oameni depăşeşte biomasa
▼ + stars: | 2020-12-10 | by ( Publika.Md - Aici Sunt Știrile | ) www.publika.md time to read: 1 min

Masa tuturor construcțiilor artificiale realizate de oemeni - clădiri, șosele, aparatură etc. - va depăși după 2020 masa totală a întregii materii vegetale și animale de pe Pământ, informează Agerpres, care citează un studiu publicat de revista Nature. Cercetarea, realizată de Weizmann Institute of Science din Israel, susţine că omenirea şi Pământul se află la „un moment de cotitură” în 2020, când masa întregii materii produse de om a ajuns egală cu masa florei şi faunei, cum ar fi copacii, plantele, animalele, bacteriile şi ciupercile. Institutul estimează că masa materiei produse de mâna omului va fi de două ori mai mare decât cea a biomasei până în 2040. Până atunci, „jungla” din beton, oţel şi plastic creată de oameni este preconizată să cântărească cel puţin două teratone.

Organizations: Nature, Weizmann Institute, Science Locations: Agerpres, Israel

☆ Junglă de beton. Masa tuturor construcțiilor create de om o va depăși pe cea a vietăților
▼ + stars: | 2020-12-10 | by ( Onixmedia Srl | ) diez.md time to read: +1 min

Institutul estimează că masa materiei produse de mâna omului va fi de două ori mai mare decât cea a biomasei până în 2040. Până atunci, jungla din beton, oțel și plastic creată de oameni este preconizată să cântărească cel puțin două teratone. Acesta a spus că studiul este, după știința sa, primul care compară masa fabricată de om cu biomasa. Rezultatele cercetării „demonstrează cât de mult s-a extins amprenta noastră globală peste măsura de la pantof”, a spus Milo. „Sperăm că odată ce avem toate aceste date șocante în fața ochilor, putem, ca specie, să ne asumăm responsabilitatea”, a mai spus acesta.

Persons: Ron Milo, Weizmann Institute ., Milo Organizations: BBC, Weizmann Institute, Science, Nature Locations: Israel

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